STAMBP Antikörper (AA 331-420) (HRP)

Produktnummer ABIN882528

Dieser Anti-STAMBP Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von STAMBP in ELISA, IHC (p) und IHC (fro). Geeignet für Maus und Ratte.

Kurzübersicht für STAMBP Antikörper (AA 331-420) (HRP) (ABIN882528)

Target: STAMBP (STAM Binding Protein (STAMBP))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAMBP Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-STAMBP Antikörper (HRP)

Bindungsspezifität: AA 331-420

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AMSH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STAMBP

Target: STAMBP (STAM Binding Protein (STAMBP))

Andere Bezeichnung: AMSH

Hintergrund:

Synonyms: Associated molecule with the SH3 domain of STAM, Endosome associated ubiquitin isopeptidase, Endosome-associated ubiquitin isopeptidase, STABP_HUMAN, STAM binding protein, STAM-binding protein, STAMBP.

Background: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.

Gen-ID: 10617